assign_peptide_type: Assign peptide type

In protti: Bottom-Up Proteomics and LiP-MS Quality Control and Data Analysis Tools

Assign peptide type

Description

Based on preceding and C-terminal amino acid, the peptide type of a given peptide is assigned. Peptides with preceeding and C-terminal lysine or arginine are considered fully-tryptic. If a peptide is located at the N- or C-terminus of a protein and fulfills the criterium to be fully-tryptic otherwise, it is also considered as fully-tryptic. Peptides that only fulfill the criterium on one terminus are semi-tryptic peptides. Lastly, peptides that are not fulfilling the criteria for both termini are non-tryptic peptides.

Usage

assign_peptide_type(
  data,
  aa_before = aa_before,
  last_aa = last_aa,
  aa_after = aa_after
)

Arguments

data	a data frame containing at least information about the preceding and C-terminal amino acids of peptides.
aa_before	a character column in the data data frame that contains the preceding amino acid as one letter code.
last_aa	a character column in the data data frame that contains the C-terminal amino acid as one letter code.
aa_after	a character column in the data data frame that contains the following amino acid as one letter code.

Value

A data frame that contains the input data and an additional column with the peptide type information.

Examples

data <- data.frame(
  aa_before = c("K", "S", "T"),
  last_aa = c("R", "K", "Y"),
  aa_after = c("T", "R", "T")
)

assign_peptide_type(data, aa_before, last_aa, aa_after)

protti documentation built on Jan. 22, 2023, 1:11 a.m.