bbcdRand | R Documentation |
Sampling algorithm for bbcd
bbcdRand(N, a, K = 2)
N |
integer for the total sample size of the trial. |
a |
nonnegative parameter which controls the degree of randomness:
For decreasing |
K |
number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment). |
A vector with the allocation sequence for a clinical trial.
It will contain a zero (resp. 1) at position i
, when patient i
is allocated to treatment A (resp. B).
A. B. Antognini and Maroussa Zagoraiou (2014) Balance and randomness in sequential clinical trials: the dominant biased coin design. Pharmaceutical Statistics 13(2), 119-127
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