Description Usage Arguments Value References

Sampling algorithm for gbcd

1 |

`N` |
integer for the total sample size of the trial. |

`rho` |
nonnegative parameter which my be adjusted according to how strongly it is
desired to balance the experiment. If |

`K` |
number of treatment groups (e.g. K=2 if we compare one experimental against one control treatment). |

A vector with the allocation sequence for a clinical trial.
It will contain a zero (resp. 1) at position `i`

, when patient `i`

is allocated to treatment A (resp. B).

R. L. Smith (1984) Sequential treatment allocation using biased coin designs.
*Journal of the Royal Statistical Society B*,
**46**, 519-543.

W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. *Wiley*,
64-65

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