randomizeR-package: Randomization for Clinical Trials

randomizeR-packageR Documentation

Randomization for Clinical Trials

Description

This tool enables the user to choose a randomization procedure based on sound scientific criteria. It comprises the generation of randomization sequences as well the assessment of randomization procedures based on carefully selected criteria. Furthermore, randomizeR provides a function for the comparison of randomization procedures.

Acknowledgement

This research is embedded in the IDeAl project, which has received funding from the European Union's Seventh Framework Programme for research, technological development and demonstration under Grant Agreement no 602552.

Author(s)

David Schindler dv.schindler@gmail.com, Diane Uschner Diane.Uschner@gmail.com, Ralf-Dieter Hilgers, Nicole Heussen, Marcia Viviane Rueckbeil marcia.rueckbeil@rwth-aachen.de

References

W. F. Rosenberger and J. M. Lachin (2002) Randomization in Clinical Trials. Wiley.

#' D. Uschner, D. Schindler, R. D. Hilgers and N. Heussen (2018). "randomizeR: An R Package for the Assessment and Implementation of Randomization in Clinical Trials." Journal of Statistical Software, 85(8), pp. 1-22. doi: 10.18637/jss.v085.i08 .

D. Schindler (2016) Assessment of Randomization Procedures in the Presence of Selection and Chronological Bias. PhD Thesis.

D. Uschner, R. D. Hilgers, N. Heussen (2018). "The impact of selection bias in randomized multi-arm parallel group clinical trials." PLOS ONE, 13(1): e0192065. doi: 10.1371/journal.pone.0192065.

M. V. Rueckbeil, R. D. Hilgers, N. Heussen (2019). "Randomization in survival studies: An evaluation method that takes into account selection and chronological bias." PLOS ONE, 14(6): e0217946. doi: 10.1371/journal.pone.0217946.

See Also

For functionality for randomization procedures, see randPar and genSeq. For the criteria for the assessment of randomization procedures, see issues. For the assessment and comparison of randomization procedures, see assess and compare.


randomizeR documentation built on Sept. 19, 2023, 1:08 a.m.