DTI: Diffusion Tensor Imaging: tract profiles and outcomes

In refund: Regression with Functional Data

Diffusion Tensor Imaging: tract profiles and outcomes

Description

Fractional anisotropy (FA) tract profiles for the corpus callosum (cca) and the right corticospinal tract (rcst). Accompanying the tract profiles are the subject ID numbers, visit number, total number of scans, multiple sclerosis case status and Paced Auditory Serial Addition Test (pasat) score.

Format

A data frame made up of

cca

A 382 x 93 matrix of fractional anisotropy tract profiles from the corpus callosum;

rcst

A 382 x 55 matrix of fractional anisotropy tract profiles from the right corticospinal tract;

ID

Numeric vector of subject ID numbers;

visit

Numeric vector of the subject-specific visit numbers;

visit.time

Numeric vector of the subject-specific visit time, measured in days since first visit;

Nscans

Numeric vector indicating the total number of visits for each subject;

case

Numeric vector of multiple sclerosis case status: 0 - healthy control, 1 - MS case;

sex

factor variable indicated subject's sex;

pasat

Numeric vector containing the PASAT score at each visit.

Details

If you use this data as an example in written work, please include the following acknowledgment: “The MRI/DTI data were collected at Johns Hopkins University and the Kennedy-Krieger Institute"

DTI2 uses mean diffusivity of the the corpus callosum rather than FA, and parallel diffusivity of the rcst rather than FA. Please see the documentation for DTI2.

References

Goldsmith, J., Bobb, J., Crainiceanu, C., Caffo, B., and Reich, D. (2011). Penalized Functional Regression. Journal of Computational and Graphical Statistics, 20, 830 - 851.

Goldsmith, J., Crainiceanu, C., Caffo, B., and Reich, D. (2010). Longitudinal Penalized Functional Regression for Cognitive Outcomes on Neuronal Tract Measurements. Journal of the Royal Statistical Society: Series C, 61, 453 - 469.

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