clade_continuous: Influential Clade Detection - Trait Evolution Continuous...
In sensiPhy: Sensitivity Analysis for Comparative Methods

Description Usage Arguments Details Value Author(s) References See Also Examples

Fits models for trait evolution of continuous characters, detecting influential clades

clade_continuous(
  data,
  phy,
  model,
  trait.col,
  clade.col,
  n.species = 5,
  n.sim = 20,
  bounds = list(),
  n.cores = NULL,
  track = TRUE,
  ...
)

`data`	Data frame containing species traits with row names matching tips in `phy`.
`phy`	A phylogeny (class 'phylo') matching `data`.
`model`	The evolutionary model (see Details).
`trait.col`	The column in the provided data frame which specifies the trait to analyse (which should be a factor with two level)
`clade.col`	The column in the provided data frame which specifies the clades (a character vector with clade names).
`n.species`	Minimum number of species in a clade for the clade to be included in the leave-one-out deletion analysis. Default is `5`.
`n.sim`	Number of simulations for the randomization test.
`bounds`	settings to constrain parameter estimates. See `fitContinuous`
`n.cores`	number of cores to use. If 'NULL', number of cores is detected.
`track`	Print a report tracking function progress (default = TRUE)
`...`	Further arguments to be passed to `fitContinuous`

This function sequentially removes one clade at a time, fits a model of continuous character evolution using fitContinuous, repeats this many times (controlled by n.sim), stores the results and calculates the effects on model parameters Currently, only binary continuous traits are supported.

Additionally, to account for the influence of the number of species on each clade (clade sample size), this function also estimates a null distribution expected for the number of species in a given clade. This is done by fitting models without the same number of species as in the given clade.The number of simulations to be performed is set by 'n.sim'. To test if the clade influence differs from the null expectation for a clade of that size, a randomization test can be performed using 'summary(x)'.

Different evolutionary models from fitContinuous can be used, i.e. BM,OU, EB, trend, lambda, kappa, delta and drift.

See fitContinuous for more details on evolutionary models.

Output can be visualised using sensi_plot.

The function tree_continuous returns a list with the following components:

call: The function call

data: The original full data frame.

full.model.estimates: Parameter estimates (rate of evolution sigsq and where applicable optpar), root state z0, AICc for the full model without deleted clades.

sensi.estimates: Parameter estimates (sigsq and optpar), (percentual) difference in parameter estimate compared to the full model (DIFsigsq, sigsq.perc, DIFoptpar, optpar.perc), AICc and z0 for each repeat with a clade removed.

null.dist: A data frame with estimates for the null distributions for all clades analysed.

errors: Clades where deletion resulted in errors.

clade.col: Which column was used to specify the clades?

optpar: Transformation parameter used (e.g. lambda, kappa etc.)

Gijsbert Werner & Gustavo Paterno

Paterno, G. B., Penone, C. Werner, G. D. A. sensiPhy: An r-package for sensitivity analysis in phylogenetic comparative methods. Methods in Ecology and Evolution 2018, 9(6):1461-1467

Yang Z. 2006. Computational Molecular Evolution. Oxford University Press: Oxford.

Harmon Luke J, Jason T Weir, Chad D Brock, Richard E Glor, and Wendell Challenger. 2008. GEIGER: investigating evolutionary radiations. Bioinformatics 24:129-131.

fitContinuous

## Not run: 
data("primates")
#Model trait evolution accounting for phylogenetic uncertainty
clade_cont<-clade_continuous(data=primates$data,phy = primates$phy[[1]], model="OU",
trait.col = "adultMass",clade.col="family",n.sim=30,n.species=10,n.cores = 2,track=TRUE)
#Print summary statistics
summary(clade_cont)
sensi_plot(clade_cont,graph="all")
sensi_plot(clade_cont,clade="Cercopithecidae",graph = "sigsq")
sensi_plot(clade_cont,clade="Cercopithecidae",graph = "optpar")
#Change the evolutionary model, tree transformation or minimum number of species per clade
clade_cont2<-clade_continuous(data=primates$data,phy = primates$phy[[1]],model="delta",
trait.col = "adultMass",clade.col="family",n.sim=30,n.species=5,n.cores = 2,track=TRUE)
summary(clade_cont2)
sensi_plot(clade_cont2)
clade_cont3<-clade_continuous(data=primates$data,phy = primates$phy[[1]],model="BM",
trait.col = "adultMass",clade.col="family",n.sim=30,n.species=5,n.cores = 2,track=TRUE)
summary(clade_cont3)
sensi_plot(clade_cont3,graph="sigsq")

## End(Not run)