Likelihood function.

Description

Likelihood function.

Usage

1
L(x, g.hat, d.hat)

Arguments

x

Matrix of gene expression data.

g.hat

Estimated additive batch effect.

d.hat

Estimated multiplicative batch effect.

Value

Likelihood estimate.

Warning

This function is not called by the user directly.

Author(s)

WE Johnson

References

W. Johnson E., L. Chen, Rabinovic, and A. Adjusting batch effects in microarray expression data using Empirical Bayes methods. Biostatistics, 8(1):118-127, January2007. ISSN 1465-4644. doi: http://dx.doi.org/10.1093/biostatistics/kxj037.

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