trialr: Clinical Trial Designs in 'rstan'

A collection of clinical trial designs and methods, implemented in 'rstan' and R, including: the Continual Reassessment Method by O'Quigley et al. (1990) <doi:10.2307/2531628>; EffTox by Thall & Cook (2004) <doi:10.1111/j.0006-341X.2004.00218.x>; and the Augmented Binary method by Wason & Seaman (2013) <doi:10.1002/sim.5867>; and more. We provide functions to aid model-fitting and analysis. The 'rstan' implementations may also serve as a cookbook to anyone looking to extend or embellish these models. We hope that this package encourages the use of Bayesian methods in clinical trials. There is a preponderance of early phase trial designs because this is where Bayesian methods are used most. If there is a method you would like implemented, please get in touch.

Package details

AuthorKristian Brock [aut, cre] (<https://orcid.org/0000-0002-3921-0166>), Trustees of Columbia University [cph]
MaintainerKristian Brock <[email protected]>
LicenseGPL (>= 3)
Version0.1.3
URL https://github.com/brockk/trialr
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("trialr")

Try the trialr package in your browser

Any scripts or data that you put into this service are public.

trialr documentation built on Jan. 9, 2020, 1:09 a.m.