Man pages for trialr
Clinical Trial Designs in 'rstan'

as.data.frame.crm_fitConvert crm_fit object to 'data.frame'.
as.data.frame.efftox_fitConvert efftox_fit object to 'data.frame'.
as.mcmc.list.crm_fitConvert 'crm_fit' to instance of 'mcmc.list'
as.mcmc.list.efftox_fitConvert 'efftox_fit' to instance of 'mcmc.list'
as_tibble.augbin_2t_1a_fitCast 'augbin_2t_1a_fit' object to 'tibble'.
as_tibble.dose_finding_pathsCast 'dose_finding_paths' object to 'tibble'.
augbin_2t_1a_fitClass used by 'trialr' to fit Wason & Seaman's Augmented...
augbin_fitClass used by 'trialr' to fit Wason & Seaman's Augmented...
binary_prob_successCalculate the binary probability of success.
careful_escalationDose selection function that practices careful escalation.
closest_to_targetGet index of element in vector with value closest to a target
crm_codified_dose_logisticCalculate codified CRM doses.
crm_dtpsCalculate dose-transition pathways for a CRM study
crm_fit-classClass of model fit by 'trialr' using the CRM dose-finding...
crm_params-classContainer class for parameters to fit the CRM models in...
crm_path_analysisFit a CRM model to the incrementally observed outcomes on a...
crm_prior_beliefsGet the prior beliefs for a CRM trial scenario.
crm_processProcess RStan samples from a CRM model.
df_parse_outcomesParse a string of dose-finding trial outcomes to binary...
dose_finding_fit-classClass of dose-finding model fit by 'trialr' using Stan.
dose_finding_path_node-classClass to hold the elements of a single dose-finding analysis...
eff_at_doseGet the number of efficacy events seen at the doses under...
efftox_analysis_to_dfEffTox analysis to data.frame
efftox_contour_plotPlot EffTox utility contours
efftox_dtpsCalculate dose-transition pathways for an EffTox study
efftox_dtps_to_dataframeCalculate dose-transition pathways for an EffTox study
efftox_fit-classClass of model fit by 'trialr' using the EffTox dose-finding...
efftox_get_toxGet the Prob(Tox) for Prob(Eff) and utility pairs
efftox_parameters_demoGet parameters to run the EffTox demo
efftox_params-classContainer class for parameters to fit the EffTox model in...
efftox_parse_outcomesParse a string of EffTox outcomes to binary vector notation.
efftox_path_analysisFit an EffTox model to the incrementally observed outcomes on...
efftox_priorsSimple class to hold prior hyperparameters for the EffTox...
efftox_processProcess RStan samples from an EffTox model
efftox_simulateRun EffTox simulations
efftox_solve_pCalculate the p-index for EffTox utility contours
efftox_superiorityGet dose-superiority matrix in EffTox
efftox_utilityGet the utility of efficacy & toxicity probability pairs
efftox_utility_density_plotPlot densities of EffTox dose utilities
get_efftox_priorsGet normal prior hyperparameters for the EffTox model.
n_at_doseGet the number of patients treated at the doses under...
parse_dose_finding_outcomesParse a string of dose-finding trial outcomes.
parse_eff_tox_dose_finding_outcomesParse a string of phase I/II dose-finding trial outcomes.
peps2_get_dataGet data to run the PePS2 trial example
peps2_processProcess RStan samples from a BEBOP model fit to PePS2 data
plot.crm_fitPlot an crm_fit
plot.efftox_fitPlot an efftox_fit
predict.augbin_2t_1a_fitPredict probability of success for given tumour size...
print.augbin_fitPrint augbin_fit object.
print.crm_fitPrint crm_fit object.
print.efftox_fitPrint efftox_fit object.
print.nbg_fitPrint nbg_fit object.
prior_predictive_augbin_2t_1aSample data from the Augmented Binary model prior predictive...
prob_successCalculate the probability of success.
prob_tox_exceedsCalculate the probability that the rate of toxicity exceeds...
ranBin2Sample pairs of correlated binary events
rlkjcorrSample LKJ correlation matrices.
spread_pathsSpread the information in dose_finding_paths object to a wide...
stan_augbinFit Wason & Seaman's Augmented Binary model for tumour...
stan_augbin_demoSimple helper function to demonstrate fitting of an Augmented...
stan_crmFit a CRM model
stan_efftoxFit an EffTox model
stan_efftox_demoFit the EffTox model presented in Thall et al. (2014)
stan_hierarchical_response_thallFit the hierarchical response model described by Thall _et...
stan_nbgFit a Neuenschwander, Branson & Gsponer logit dose-finding...
stan_peps2Fit the P2TNE model developed for the PePS2 trial to some...
summary.crm_fitObtain summary of an crm_fit
summary.efftox_fitObtain summary of an efftox_fit
total_weight_at_doseGet the total weight of patient outcomes at the doses under...
tox_at_doseGet the number of toxicity events seen at the doses under...
trialr-packageThe 'trialr' package.
trialr_simulateRun a simulation study.
weights_at_doseGet the weights of patient outcomes at the doses under...
trialr documentation built on April 1, 2023, 12:03 a.m.