crm_codified_dose_logistic: Calculate codified CRM doses.

In trialr: Clinical Trial Designs in 'rstan'

Calculate codified CRM doses.

Description

Calculate the codified CRM doses that map to probability of toxicity prob_tox in a logistic model with expected values for intercept and gradient. I.e. find x[i] such that logit(p[i]) = \alpha + \beta x[i], were p is prob_tox.

Usage

crm_codified_dose_logistic(prob_tox, alpha_mean, beta_mean)

Arguments

prob_tox	Numeric vector, seek codified doses that yield these probabilities of toxicity.
alpha_mean	Numeric, expected value of intercept.
beta_mean	Numeric, expected value of gradient with respect to dose.

Value

Numeric vector of codified doses.

Examples

skeleton <- c(0.05, 0.1, 0.2, 0.5)
crm_codified_dose_logistic(skeleton, 1, 0)
crm_codified_dose_logistic(skeleton, 3, 0.5)

trialr documentation built on April 1, 2023, 12:03 a.m.