augbin_2t_1a_fit: Class used by 'trialr' to fit Wason & Seaman's Augmented...

In trialr: Clinical Trial Designs in 'rstan'

Class used by trialr to fit Wason & Seaman's Augmented Binary method in single arm trials with two post-baseline tumour assessments.

Description

Class used by trialr to fit Wason & Seaman's Augmented Binary method in single arm trials with two post-baseline tumour assessments.

Usage

augbin_2t_1a_fit(num_patients, tumour_size, non_shrinkage_failure, fit)

Arguments

num_patients	Integer, the number of patients analysed.
tumour_size	matrix-like object containing tumour size measures, with rows representing patients and columns representing chronological assessment points. Column one is baseline.
non_shrinkage_failure	matrix-like object containing logical indicators of non-shrinkage failure, with rows representing patients and columns representing chronological assessment points.
fit	An object of class stanfit, containing the posterior samples.

References

Wason JMS, Seaman SR. Using continuous data on tumour measurements to improve inference in phase II cancer studies. Statistics in Medicine. 2013;32(26):4639-4650. doi:10.1002/sim.5867

Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). European Journal of Cancer. 2009;45(2):228-247. doi:10.1016/j.ejca.2008.10.026

See Also

augbin_fit stan_augbin

trialr documentation built on April 1, 2023, 12:03 a.m.