desc_dch: Dechallenge descriptive
| desc_dch | R Documentation |
Dechallenge descriptive
Description
![[Stable]](../help/figures/lifecycle-stable.svg)
Computes positive
dechallenge counts over a set of adr and drug pairs.
Usage
desc_dch(.data, drug_s = "drug1", adr_s = "adr1")
Arguments
.data |
A |
drug_s |
A character vector, the drug column(s) |
adr_s |
A character vector, the adverse drug reaction column(s). |
Details
Counts are provided at the case level (not the drug-adr pair level).
Positive dechallenge refers to cases where drug was withdrawn or
dose-reduced and reaction abated (in part or in full).
You will need a link data.table, see link_, on which
you have added drugs and adrs with add_drug() and add_adr().
Value
A data.table with one row per drug-adr pair.
-
drug_sandadr_s, same as input -
pos_dch, number of positive dechallenge cases
See Also
link_, add_drug(), add_adr(), desc_tto(), desc_rch()
Examples
link_ <-
link_ |>
add_drug(
d_code = ex_$d_groups_drecno,
drug_data = drug_
) |>
add_adr(
a_code = ex_$a_llt,
adr_data = adr_
)
desc_dch(link_,
drug_s = "pd1",
adr_s = "a_colitis")
# you can vectorize over multiple adrs and drugs
desc_dch(link_,
drug_s = c("pd1", "pdl1"),
adr_s = c("a_colitis", "a_pneumonitis"))
