desc_outcome: Outcome descriptive

In vigicaen: 'VigiBase' Pharmacovigilance Database Toolbox

Outcome descriptive

Description

Compute outcome description over a set of adr and drugs.

Usage

desc_outcome(.data, drug_s = "drug1", adr_s = "adr1")

Arguments

.data	An adr data.table. See adr_
drug_s	A character vector, the drug column(s)
adr_s	A character vector, the adverse drug reaction column(s).

Details

You need an adr data.table. Be careful that you cannot directly filter adr data.table on drugs! You first have to add drug columns to adr, with add_drug(). The function reports the worst outcome into consideration for a given case, if many are reported. Outcomes, from best to worst are:

• Recovered/resolved

• Recovering/resolving

• Recovered/resolved with sequelae

• Not recovered/not resolved

• Fatal

• Died- unrelated to reaction

• Died- reaction may be contributory

See vignette("descriptive") for more details.

Value

A data.table with one row per drug-adr pair.

• drug_s and adr_s, same as input

• n_cas, number of cases for each category

• out_label, the worst outcome for this drug-adr pair

See Also

adr_, add_drug(), add_adr()

Examples

adr_ <-
  adr_ |>
  add_drug(
    d_code = ex_$d_groups_drecno,
    drug_data = drug_
  ) |>
  add_adr(
    a_code = ex_$a_llt,
    adr_data = adr_
  )

desc_outcome(
  adr_,
  drug_s = "pd1",
  adr_s = "a_colitis"
  )

# you can vectorize over multiple adrs and drugs

desc_outcome(
  adr_,
  drug_s = c("pd1", "pdl1"),
  adr_s = c("a_colitis", "a_pneumonitis")
  )

vigicaen documentation built on April 3, 2025, 8:55 p.m.