desc_tto: Time to onset descriptive

In vigicaen: 'VigiBase' Pharmacovigilance Database Toolbox

Time to onset descriptive

Description

desc_tto() provides a drug-adr pair description of time to onset.

Usage

desc_tto(.data, adr_s, drug_s, tto_time_range = 1, ...)

Arguments

.data	A link data.table. See link_.
adr_s	A character string. The name of the adr column. (see details)
drug_s	A character string. The name of the drug column. (see details)
tto_time_range	Incertitude range of Time to onset, in days. Defaults to 1 as recommended by umc
...	Additional parameters to be passed to desc_cont(). E.g. format, digits...

Details

Description of time (maximum available time) between drug initiation and event onset. This runs at the drug-adr pair level. Internally, it uses extract_tto() and desc_cont(), You will need a link data.table, see link_, on which you have added drugs and adrs with add_drug() and add_adr(). you can supply extra arguments to desc_cont() with .... Uppsala Monitoring Centre recommends to use only cases where the incertitude on time to onset is less than 1 day. You can change this with tto_time_range.

Value

A data.table with one row per drug-adr pair

• A descriptive of time to onsets for this combination (column tto_max).

See Also

link_, extract_tto(), add_drug(), add_adr(), desc_dch(), desc_rch()

Examples

link_ <-
  link_ |>
  add_drug(
    d_code = ex_$d_groups_drecno,
    drug_data = drug_
  ) |>
  add_adr(
    a_code = ex_$a_llt,
    adr_data = adr_
  )

desc_tto(.data = link_,
         adr_s = "a_colitis",
         drug_s = "pd1")


desc_tto(.data = link_,
         adr_s = c("a_colitis", "a_pneumonitis"),
         drug_s = c("pd1", "ctla4"))

vigicaen documentation built on April 3, 2025, 8:55 p.m.