sad: Single Ascending Dose Data Set

sadR Documentation

Single Ascending Dose Data Set


Model generated PK data to mimic an orally administered small molecule. Simulated single dose administration ranging from 100 mg to 1600 mg.




A data frame with the following 16 columns:

column 1: ID numeric; unique subject ID
column 2: TIME numeric; time relative to first drug administration
column 3: NOMTIME numeric; nominal time
column 4: TIMEUNIT character; unit of TIME
column 5: AMT numeric; dosing amount (for dosing events) in mg
column 6: LIDV numeric; observation on a linear scale (observation type determined by CMT), units determined by EVENTU column
column 7: MDV numeric; missing dependent variable
(1 if missing, 0 otherwise)
column 8: CMT integer; compartment number (determines observation type):
CMT 1 = Dosing event
CMT 2 = PK concentration
column 9: NAME character; description of event
column 10: EVENTU character; unit for observation
column 11: CENS integer; censored values (0 = not censored, 1 = censored)
column 12: EVID integer; event ID (0 = observation, 1 = dosing event)
column 13: WEIGHTB numeric; baseline body weight (kg)
column 14: SEX character; sex
column 15: TRTACT factor; treatment group label
column 16: DOSE numeric; randomized dose in mg received

xgxr documentation built on March 31, 2023, 11:46 p.m.