sad: Single Ascending Dose Data Set

Description Usage Format


Model generated PK data to mimic an orally administered small molecule. Simulated single dose administration ranging from 100 mg to 1600 mg.




A data frame with the following 16 columns:

column 1: ID numeric; unique subject ID
column 2: TIME numeric; time relative to first drug administration
column 3: NOMTIME numeric; nominal time
column 4: TIMEUNIT character; unit of TIME
column 5: AMT numeric; dosing amount (for dosing events) in mg
column 6: LIDV numeric; observation on a linear scale (observation type determined by CMT), units determined by EVENTU column
column 7: MDV numeric; missing dependent variable
(1 if missing, 0 otherwise)
column 8: CMT integer; compartment number (determines observation type):
CMT 1 = Dosing event
CMT 2 = PK concentration
column 9: NAME character; description of event
column 10: EVENTU character; unit for observation
column 11: CENS integer; censored values (0 = not censored, 1 = censored)
column 12: EVID integer; event ID (0 = observation, 1 = dosing event)
column 13: WEIGHTB numeric; baseline body weight (kg)
column 14: SEX character; sex
column 15: TRTACT factor; treatment group label
column 16: DOSE numeric; randomized dose in mg received

xgxr documentation built on April 23, 2021, 1:07 a.m.