Mendelian is an R package that can be used to filter sequencing variants. It enables filtering for both dominant and recessive traits, with a wide variety of options (including reduced penetrance and detectance).
This package can be installed from github using:
require(devtools) devtools::install_github("BartBroeckx/Mendelian", build_vignettes=TRUE)
Detailed examples are available in the vignette.
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