gDom: Variant filtering with dominant inheritance considering...

In BartBroeckx/Mendelian: Variant Analysis for Mendelian Disorders

Description

gDom should be used to filter variants under a dominant mode of inheritance when common functional units (a gene, an exon, ...) should be considered.

Usage

gDom(x, y)

Arguments

x	the case(s).
y	optional, the control(s).

Details

gDom checks for common functional units within cases. If variants from control(s) are present, they can be used to filter variants from the cases. In addition, various detectance and penetrance parameters can be specified during the processing.

Before using this function, each file from each case should have been processed by CLCfile or VCFfile with annot.

Author(s)

Bart Broeckx

Examples

CLCfile1proc <-CLCfile(CLCfile1, "Coding.region.change", TRUE, "; ")
CLCfile2proc <-CLCfile(CLCfile2, "Coding.region.change", TRUE, "; ")
 output <- gDom("CLCfile1proc", "CLCfile2proc")
 output
 output <- gDom(c("CLCfile1proc","CLCfile2proc"))
 output

BartBroeckx/Mendelian documentation built on May 5, 2019, 10:27 a.m.