Man pages for BinDuan/MASCOT
Model-based Analysis of Single cell CRISPR knockOuT screening
| Batch_adjust | Adjusting batch effect. |
| Cell_filtering | Filtering cells and calculating the overall knockout... |
| Cell_qc | Quality control for single-cell CRISPR screening data. |
| Get_distribution_diff | Calcualting topic distribution difference between case and... |
| Get_high_var_genes | Identify highly dispersion differentially expressed genes. |
| Get_offtarget | Evaluating the offtarget effect of sgRNAs. |
| Get_topics | Obtaining the result by performing topic model. |
| Input_preprocess | Checking the input data. |
| Input_preprocess_10X | Checking the input data if the data was generated with 10X. |
| Plot_cell_topic | Plotting a heatmap showing the distribution of cells in each... |
| Plot_filtering_overview | plot cells filtered by each filtering steps. |
| Rank_diff | Obtaining important knockouts between two different... |
| Rank_overall | Obtaining the overall perturbation effect ranking list. |
| Rank_topic_specific | Obtaining the topic-specific ranking list. |
| Topic_func_anno | Annotating each topic's function. |
