Rank_diff: Obtaining important knockouts between two different...

In BinDuan/MASCOT: Model-based Analysis of Single cell CRISPR knockOuT screening

Description

Obtaining knockouts with highly different ranking between two different conditions for the same type cellls.

Usage

Rank_diff(rankOverall_result_summary_condition1, rankOverall_result_summary_condition2, difference_threshold = 0.5, plot = TRUE, plot_path = "~/rank_diff.pdf")

Arguments

rankOverall_result_summary_condition1	The overall perturbation impact ranking list when knockout cells are under condition 1.
rankOverall_result_summary_condition2	The overall perturbation impact ranking list when knockout cells are under condition 2.
difference_threshold	The threshold ratio of the ranking difference in all knockouts between two conditions. The default is 0.5 .
plot	TURE by default. If FAALSE, don't plot the graph.
plot_path	The path of graph you plot. It works only when "plot" is TURE.

Value

A dataframe showing knockouts with the highly different ranking and their corresponding ranking difference.

Author(s)

Bin Duan

BinDuan/MASCOT documentation built on May 23, 2019, 2:42 p.m.