Batch_adjust | Adjusting batch effect. |
Cell_filtering | Filtering cells and calculating the overall knockout... |
Cell_qc | Quality control for single-cell CRISPR screening data. |
Get_distribution_diff | Calcualting topic distribution difference between case and... |
Get_high_var_genes | Identify highly dispersion differentially expressed genes. |
Get_offtarget | Evaluating the offtarget effect of sgRNAs. |
Get_topics | Obtaining the result by performing topic model. |
Input_preprocess | Checking the input data. |
Input_preprocess_10X | Checking the input data if the data was generated with 10X. |
Plot_cell_topic | Plotting a heatmap showing the distribution of cells in each... |
Plot_filtering_overview | plot cells filtered by each filtering steps. |
Rank_diff | Obtaining important knockouts between two different... |
Rank_overall | Obtaining the overall perturbation effect ranking list. |
Rank_topic_specific | Obtaining the topic-specific ranking list. |
Topic_func_anno | Annotating each topic's function. |
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