calculateSSMD: Calculate strictly standardized mean difference (SSMD)

In CeMOS-Mannheim/MALDIcellassay: Automated MALDI Cell Assays Using Dose-Response Curve Fitting

Calculate strictly standardized mean difference (SSMD)

Description

Calculate strictly standardized mean difference (SSMD)

Usage

calculateSSMD(res, nConc = 2)

Arguments

res	Object of class MALDIassay
nConc	Numeric, number of top and bottom concentrations to be used to calculate the pseudo positive and negative control.

Details

The strictly standardized mean difference (SSMD) is a measure of effect size. It is the mean divided by the standard deviation of a difference between the positive and negative control.

\gamma=\frac{\mid\mu_n - \mu_p\mid}{\sqrt{\sigma_n^2 + \sigma_p^2}}

The SSMD can be easily be interpreted as it denotes the difference between positve and negative controls in units of standard deviation.

Value

Numeric vector of strictly standardized mean differences (SSMD)

Examples

# see example for `fitCurve()` to see how this data was generated
data(Blank2022res)

calculateSSMD(Blank2022res, nConc = 2)       

CeMOS-Mannheim/MALDIcellassay documentation built on Jan. 24, 2025, 11:17 p.m.