get95Int: Function get95Int
In CshlSiepelLab/ACE: Analysis of CRISPR Essentiality in R
Description
Usage
Arguments
Value
Description
Returns the 95
derived from an optimized parameter's hessian.
Variation is calculated as var = 1/(-Hessian) = 1/(FI), as the inverse
of the Fisher information matrix is an estimator of the asymptotic
covariance matrix. Assuming a normal distribution (questionable),
Usage
1
get95Int(user_hessian, user_par)
Arguments
user_hessian
Hessian matrix, returned from optim with hessian = T
user_par
Value of the optimized parameter estimate; used to calculate
the confidence interval values.
Value
Returns 95
CshlSiepelLab/ACE documentation built on Sept. 10, 2021, 11:21 p.m.
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Description Usage Arguments Value
Description
Returns the 95 derived from an optimized parameter's hessian. Variation is calculated as var = 1/(-Hessian) = 1/(FI), as the inverse of the Fisher information matrix is an estimator of the asymptotic covariance matrix. Assuming a normal distribution (questionable),
Usage
1 | get95Int(user_hessian, user_par)
|
Arguments
user_hessian |
Hessian matrix, returned from optim with hessian = T |
user_par |
Value of the optimized parameter estimate; used to calculate the confidence interval values. |
Value
Returns 95
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