optFg: Function optFg: By-gene essentiality optimization.

In CshlSiepelLab/ACE: Analysis of CRISPR Essentiality in R

Description

Function optFg: By-gene essentiality optimization.

Usage

optFg(
  startEss,
  sampleSubsets,
  sample_effects,
  guide_efficiency,
  geneList,
  write_log,
  user_DataObj,
  user_ModelObj,
  ncpus = NA
)

Arguments

startEss	Starting gene essentiality.
sampleSubsets	Sample groupings into test, ctrl, and 'all' panels.
sample_effects	By-sample parameters.
guide_efficiency	By-guide efficiency parameter.
geneList	Genes to evaluate sequentially in this function call.
write_log	Function to write to central log file.
user_DataObj	DataObject containing count data to analyze.
user_ModelObj	ModelObject with pre-processed model parameters.
ncpus	Number of threads to use in parallel optimization; if not specified, will be auto-detected.

CshlSiepelLab/ACE documentation built on Sept. 10, 2021, 11:21 p.m.