transcript_archetypes: transcript_archetypes

Description Usage Arguments Value

View source: R/transcript_archetypes.R

Description

Contructs an object that holds the transcript archetypes models

Usage

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transcript_archetypes(
  transcripts,
  bigwig_plus,
  bigwig_minus,
  flank = 5000,
  abundance_filter = 100,
  mask = c(1000, 1000),
  abundance_err_func = c("identity")
)

Arguments

transcripts

a GRanges-class object containing a pre-filtered list of transcripts that show a clear signal that arises from only that transcript with negligible signal from other sources

bigwig_plus

polymerase density signal from the plus strand

bigwig_minus

polymerase density signal from the minus strand

flank

the length of the flanking region for which data is collected for use in simulation

abundance_filter

minimal abundance value for a viable archetype gene, all transcripts with an estimated abundance less than this are removed (default = 100)

mask

a two element vector containing the number of bases to ignore at the head and tail of the transcript when estimating abundance

abundance_err_func

Error function to use when estimating abundance (defaults to identity)

Value

a transcript_archetypes-class object


CshlSiepelLab/nascentRNASim documentation built on Dec. 17, 2021, 3:08 p.m.