curated_BAGEL_nonEssential: Curated Reference Core fitness essential genes

curated_BAGEL_nonEssentialR Documentation

Curated Reference Core fitness essential genes

Description

A list of reference core fitness essential genes assembled from multiple RNAi studies used as classification template by the BAGEL algorithm to call gene depletion significance [1] and filtered as shown in [2].

Usage

data(curated_BAGEL_nonEssential)

Format

A vector of strings containing HGNC symbols of curated reference core fitness essential genes.

References

[1] BAGEL: a computational framework for identifying essential genes from pooled library screens. Traver Hart and Jason Moffat. BMC Bioinformatics, 2016 vol. 17 p. 164.

[2] Behan, F.M., Iorio, F., Picco, G. et al. Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens. Nature 568, 511–516 (2019).

See Also

curated_BAGEL_essential

Examples

data(curated_BAGEL_nonEssential)
head(curated_BAGEL_nonEssential)

DepMap-Analytics/CoRe documentation built on July 6, 2022, 8:01 a.m.