curated_BAGEL_nonEssential | R Documentation |
A list of reference core fitness essential genes assembled from multiple RNAi studies used as classification template by the BAGEL algorithm to call gene depletion significance [1] and filtered as shown in [2].
data(curated_BAGEL_nonEssential)
A vector of strings containing HGNC symbols of curated reference core fitness essential genes.
[1] BAGEL: a computational framework for identifying essential genes from pooled library screens. Traver Hart and Jason Moffat. BMC Bioinformatics, 2016 vol. 17 p. 164.
[2] Behan, F.M., Iorio, F., Picco, G. et al. Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens. Nature 568, 511–516 (2019).
curated_BAGEL_essential
data(curated_BAGEL_nonEssential) head(curated_BAGEL_nonEssential)
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