complete_m: Harmonizes the matrix of cell expression profiles with...

In LucaGiudice/Esearch3D: Leveraging gene expression and chromatin architecture to predict intergenic enhancers

Description

Remove all the genes that don't match between the cell expression profiles and the nodes inside the network

Usage

complete_m(m_profiles, net)

Arguments

m_profiles	numeric matrix of profiles, rows are genes, column is a cell or sample, value is numeric indicating a gene expression in a cell column and profile
net	adjacency matrix of the CIN network (it has to contain nodes with the same names of genes characterizing the input cell profiles)

Details

Given an expression matrix of one or multiple profiles at the columns and genes located at the rows: The method keeps only the genes that exist also in the network (CIN) This because only existing genes in the cell profile can give information to the corresponding nodes in the network and allow the propagation

Value

matrix of profiles without the rows that are not represented by a node in the network

LucaGiudice/Esearch3D documentation built on Dec. 17, 2021, 1:12 a.m.