estimate_trait_sd: Estimate trait SD by obtaining beta estimates from z-scores...

View source: R/transform.R

estimate_trait_sdR Documentation

Estimate trait SD by obtaining beta estimates from z-scores and finding the ratio with original beta values

Description

Assumes that sample size and allele frequency is correct for each SNP, and that allele frequency gives a reasonable estimate of the variance of the SNP.

Usage

estimate_trait_sd(b, se, n, p)

Arguments

b

vector of effect sizes.

se

vector of standard errors.

n

vector of sample sizes.

p

vector of allele frequencies.

Value

Vector of sd estimates for each association.


MRCIEU/TwoSampleMR documentation built on Sept. 28, 2024, 6:51 p.m.