data-dds: Gene expression data

ddsR Documentation

Gene expression data

Description

The object contains the gene expression data after differential gene expression analysis performed with DESeq2 R/Bioconductor package. The preprocessing of the RNA-Seq data included read alignment to the human reference genome (GRCh 37.1 / hg 19; STAR version 2.3.0), and read counting done with htseq-count (default mode union).

Usage

dds

Format

"DESeqDataSet" object with 136 CLL samples and 63677 features.

Author(s)

Sascha Dietrich

References

Love MI, Huber W, and Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol. 2014;15(12):550

Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, and Gingeras TR. STAR: ultrafast universal RNA-seq aligner. Bioinformatics. 2013;29(1):15-21

Anders S, Pyl PT, and Huber W. HTSeq–a Python framework to work with high-throughput sequencing data. Bioinformatics. 2015;31(2):166-9


MalgorzataOles/BloodCancerMultiOmics2017 documentation built on March 29, 2024, 2:29 p.m.