Pasquali-lab/UMI4Cats: UMI4Cats: Processing, analysis and visualization of UMI-4C chromatin contact data

UMI-4C is a technique that allows characterization of 3D chromatin interactions with a bait of interest, taking advantage of a sonication step to produce unique molecular identifiers (UMIs) that help remove duplication bias, thus allowing a better differential comparsion of chromatin interactions between conditions. This package allows processing of UMI-4C data, starting from FastQ files provided by the sequencing facility. It provides two statistical methods for detecting differential contacts and includes a visualization function to plot integrated information from a UMI-4C assay.

Getting started

Package details

Bioconductor views Alignment Coverage Normalization Preprocessing QualityControl Sequencing Visualization
Maintainer
LicenseArtistic-2.0
Version1.13.0
URL https://github.com/Pasquali-lab/UMI4Cats
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("Pasquali-lab/UMI4Cats")
Pasquali-lab/UMI4Cats documentation built on March 23, 2024, 9:42 p.m.