examples/Rules-class-IncrementsRelativeDLTCurrent.R

In Roche/crmPack: Object-Oriented Implementation of CRM Designs

# As example, here is the rule for:
# maximum doubling the dose if no DLTs were observed at the current dose
# or maximum increasing the dose by 1.33 if 1 or 2 DLTs were observed at the current dose
# or maximum increasing the dose by 1.22 if 3 or more DLTs were observed.

my_increments <- IncrementsRelativeDLTCurrent(
  intervals = c(0, 1, 3),
  increments = c(1, 0.33, 0.2)
)