def_initial: Define initial values of parameters for clustering

Description Usage Arguments Value Author(s)

View source: R/def_initial.R

Description

Defines initial values of model parameters in est_lucid, sem_lucid , & tune_lucid fitting.

Usage

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def_initial(
  init_b = NULL,
  init_m = NULL,
  init_s = NULL,
  init_g = NULL,
  init_pcluster = NULL
)

Arguments

init_b

Initial model parameters of β, genetic effects parameter: K*(ncol(G)+1) dimensional matrix, each row refers to a latent cluster and the first column is the intercept.

init_m

Initial model parameters of μ, biomarker mean effects parameters: K*ncol(Z) dimensional matrix, each row refers to a latent cluster.

init_s

Initial model parameters of Σ, biomarker covariance matrix: a list of K ncol(Z)*ncol(Z) matrices.

init_g

Initial model parameters of γ, outcome effects parameter: a vector with a length of K for binary Y or 2K for continuous Y. For binary Y, they are log odds in K clusters; for continuous Y, they are K cluster-specific means followed by standard deviations in K clusters.

init_pcluster

Initial probabilities of latent clusters.

Value

A list of initial model parameters will be returned for integrative clustering.

Author(s)

Cheng Peng, Zhao Yang, David V. Conti


USCbiostats/LUCid documentation built on Feb. 22, 2020, 8:57 p.m.