MSstatsTMT: MSstatsTMT: A package for protein significance analysis in...

MSstatsTMTR Documentation

MSstatsTMT: A package for protein significance analysis in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling

Description

A set of tools for detecting differentially abundant peptides and proteins in shotgun mass spectrometry-based proteomic experiments with tandem mass tag (TMT) labeling.

functions

  • PDtoMSstatsTMTFormat : generates MSstatsTMT required input format for Proteome discoverer output.

  • MaxQtoMSstatsTMTFormat : generates MSstatsTMT required input format for MaxQuant output.

  • SpectroMinetoMSstatsTMTFormat : generates MSstatsTMT required input format for SpectroMine output.

  • OpenMStoMSstatsTMTFormat : generates MSstatsTMT required input format for OpenMS output.

  • proteinSummarization : summarizes PSM level quantification to protein level quantification.

  • dataProcessPlotsTMT : visualizes for explanatory data analysis.

  • groupComparisonTMT : tests for significant changes in protein abundance across conditions.

Author(s)

Maintainer: Devon Kohler kohler.d@northeastern.edu

Authors:

See Also

Useful links:


Vitek-Lab/MSstatsTMT documentation built on Nov. 18, 2024, 11:30 a.m.