processSignatures: Processes signatures on input

In YosefLab/FastProjectR: Functional interpretation of single cell RNA-seq latent manifolds

Processes signatures on input

Description

Removes genes that don't match a gene in the expression matrix Drops signatures with less than 'minSignatureGenes' matching genes

Usage

processSignatures(sigData, exprData, minSignatureGenes, sig_gene_threshold)

Arguments

sigData	list of signature objects
exprData	gene expression matrix
minSignatureGenes	minimum number of genes a signature must match in the expression matrix in order to be retained
sig_gene_threshold	Proportion of cells that a gene must be detected in (nonzero) to be used in signature score calculations.

Value

processedSigData list of signature objects

YosefLab/FastProjectR documentation built on Feb. 15, 2023, 6:21 a.m.