#' @title Latin Square Design
#'
#' @description Test for Significant Treatment effects and Differential Effects of Treatment Contrasts for a LSD
#'
#' @param resp The response variable vector
#' @param trt The treatment vector
#' @param rows A vector containing the row indices of a LSD
#' @param cols A vector containing the column indices of a LSD
#' @param los Level of significance (Default is 0.05)
#'
#' @return A list containing - ANOVA Table, Decision Table, Rejected Pairs, Mean Square Error, Critical Point
#'
#' @details In experimental designs if test of differential effect gets rejected we might be interested in analyzing which pair of treatments is behind the rejection.
#' For LSD we need to calculate the estimate of the treatment contrast (tau_k - tau_k') and test H0: tau_{k} = tau_{k'} for plausible rejection.
#' The estimate of (tau_k - tau_k') is (y_{00k} - y_{00k'}) which follows N(tau_j - tau_j', 2*sigma^2/v).
#' Under H_0, the test statistic (y_{00k} - y_{00k'})/sqrt(2*MSE/v) follows t_{(v-1)(v-2)}.
#'
#' @author Anik Chakraborty
#' @section Special Thanks: Professor Surupa Chakraborty and Professor Debjit Sengupta for helping me in building the concepts of Design of Experiments.
#' Professor Madhura Dasgupta for guiding me in R programming.
#
#' @seealso For CRD \code{\link{diff_eff.crd}}, for RBD \code{\link{diff_eff.rbd}}
#'
#' @export diff_eff.lsd
diff_eff.lsd = function(resp, trt, rows, cols, los = 0.05)
{
# Latin Square Design
if (!is.numeric(resp))
stop("The response variable must be a numeric vector")
l = c(length(resp), length(trt), length(rows), length(cols))
if (any(diff(l) != numeric(3)))
stop("Response, Treatments, Rows and Column vector must have same lenght")
lsd = data.frame(Response = resp,
Treatments = factor(trt),
Rows = factor(rows),
Columns = factor(cols))
n = nrow(lsd) # Total observations
mu_hat = mean(lsd$Response) # Grand Mean
model = summary(stats::aov(Response ~ Rows + Columns +
Treatments, lsd))
# Treatment wise Data
trt = dplyr::summarise(dplyr::group_by(lsd, Treatments),
Means = mean(Response))
y_bar = trt$Means; v = nrow(trt)
# MSE: Estimate of variance in the model
MSE = model[[1]]$`Mean Sq`[4]
# Critical value
crit = stats::qt(los/2, (v-1)*(v-2), lower.tail = F)
# Initializing the decision table
eff = data.frame(Pairs = 0, T_obs = 0, Decision = 0)
k = 1
for (i in seq_len(v-1))
for (j in (i+1):v)
{
# Test Statistic
Test_stat = (y_bar[i] - y_bar[j])/sqrt(2 * MSE/v)
if (abs(Test_stat) > crit)
{
dec = "***"
} else dec = "-"
eff[k,] = c(paste0("(", i, ",", j, ")"),
signif(Test_stat, 3), dec)
k = k+1
}
# Rejected Pairs
rej_pair = dplyr::select(dplyr::filter(eff, Decision == "***"), Pairs)
# Output table
output = list(`ANOVA Table` = model,
Means = as.data.frame(trt),
Critical_Value = paste("The critical value for the pairwise test:", signif(crit, 3)),
Decision_Table = eff,
Rejected_pairs = rej_pair,
`No. of rejected pairs` = nrow(rej_pair))
return(output)
}
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