azampvd/DrugDiseaseNet: A Systems Biology Approach for Drug Repurposing
Generates a drug-disease network (DDN) composed of the genes that are most likely perturbed by a drug. By performing a system-level analysis on this network using disease gene expression signatures and drug-exposure gene expression signatures, the amount of perturbation caused by a drug on the genes can be estimated. This can help to identify the associations to a disease of interest.
Getting started
Browse package contents
Package details |
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| Author | Azam Peyvandipour, Sorin Draghici |
| Bioconductor views | GeneExpression GraphAndNetwork KEGG Microarray Network Pathways SystemsBiology |
| Maintainer | Azam Peyvandipour <azam.peyvandipour@wayne.edu> |
| License | GPL (>=3) |
| Version | 0.99.3 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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