updateGlobalGraph: keggGlobalGraph: Construct global graph of KEGG signaling...
In azampvd/DrugDiseaseNet: A Systems Biology Approach for Drug Repurposing

Description Usage Arguments Details Value Author(s) References See Also Examples

keggGlobalGraph: Construct global graph of KEGG signaling pathways.

1 2	updateGlobalGraph(globalGraph, edgesToremove = list(c("hsa:6657", "hsa:79923")))

`globalGraph`	KEGG global graph as object of type `graphNEL`
`edgesToremove`	An object of class `list` encoding edges need to be removed from the graph

See cited document for more details.

An object of class graphNEL encoding the KEGG global graph information.

Azam Peyvandipour and Sorin Draghici

#' Draghici S., et.al.: "A systems biology approach for pathway level analysis". Genome Research, 17, 2007.

keggPathwayGraphs, keggGlobalGraph

library(graph)
gg<-keggGlobalGraph()
class(edges(gg))
length(unlist(edges(gg)))
allEdges<-edges(gg)
allEdges$`hsa:2065`
ggUpdated<-updateGlobalGraph(gg,edgesToremove=
list(c("hsa:2065","hsa:2549"),c("hsa:2065","hsa:25759")))
length(unlist(edges(ggUpdated)))