azampvd/DrugDiseaseNet: A Systems Biology Approach for Drug Repurposing

Generates a drug-disease network (DDN) composed of the genes that are most likely perturbed by a drug. By performing a system-level analysis on this network using disease gene expression signatures and drug-exposure gene expression signatures, the amount of perturbation caused by a drug on the genes can be estimated. This can help to identify the associations to a disease of interest.

Getting started

Package details

AuthorAzam Peyvandipour, Sorin Draghici
Bioconductor views GeneExpression GraphAndNetwork KEGG Microarray Network Pathways SystemsBiology
MaintainerAzam Peyvandipour <[email protected]>
LicenseGPL (>=3)
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
azampvd/DrugDiseaseNet documentation built on Oct. 18, 2017, 6:14 p.m.