est_cond: generate conditional summary stats
In chr1swallace/coloc: Colocalisation Tests of Two Genetic Traits
est_cond R Documentation
generate conditional summary stats
Description
Internal helper function for est_all_cond
Usage
est_cond(x, LD, YY, sigsnps, xtx = NULL)
Arguments
x
coloc dataset
LD
named matrix of r
YY
sum((Y-Ybar)^2)
sigsnps
names of snps to jointly condition on
xtx
optional, matrix X'X where X is the genotype matrix. If
not available, will be estimated from LD, MAF, beta and sample
size (the last three should be part of the coloc dataset)
Value
data.table giving snp, beta and varbeta on remaining snps
after conditioning
Author(s)
Chris Wallace
chr1swallace/coloc documentation built on April 13, 2024, 1:05 a.m.
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| est_cond | R Documentation |
generate conditional summary stats
Description
Internal helper function for est_all_cond
Usage
est_cond(x, LD, YY, sigsnps, xtx = NULL)
Arguments
x |
coloc dataset |
LD |
named matrix of r |
YY |
sum((Y-Ybar)^2) |
sigsnps |
names of snps to jointly condition on |
xtx |
optional, matrix X'X where X is the genotype matrix. If not available, will be estimated from LD, MAF, beta and sample size (the last three should be part of the coloc dataset) |
Value
data.table giving snp, beta and varbeta on remaining snps after conditioning
Author(s)
Chris Wallace
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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