sdY.est: Estimate trait variance, internal function
In chr1swallace/coloc: Colocalisation Tests of Two Genetic Traits
sdY.est R Documentation
Estimate trait variance, internal function
Description
Estimate trait standard deviation given vectors of variance of coefficients, MAF and sample size
Usage
sdY.est(vbeta, maf, n)
Arguments
vbeta
vector of variance of coefficients
maf
vector of MAF (same length as vbeta)
n
sample size
Details
Estimate is based on var(beta-hat) = var(Y) / (n * var(X))
var(X) = 2maf(1-maf)
so we can estimate var(Y) by regressing n*var(X) against 1/var(beta)
Value
estimated standard deviation of Y
Author(s)
Chris Wallace
chr1swallace/coloc documentation built on April 13, 2024, 1:05 a.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
| sdY.est | R Documentation |
Estimate trait variance, internal function
Description
Estimate trait standard deviation given vectors of variance of coefficients, MAF and sample size
Usage
sdY.est(vbeta, maf, n)
Arguments
vbeta |
vector of variance of coefficients |
maf |
vector of MAF (same length as vbeta) |
n |
sample size |
Details
Estimate is based on var(beta-hat) = var(Y) / (n * var(X)) var(X) = 2maf(1-maf) so we can estimate var(Y) by regressing n*var(X) against 1/var(beta)
Value
estimated standard deviation of Y
Author(s)
Chris Wallace
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.