Compute R from fractional changes of steady states
| 1 | R_fun(pars_opt, perturbation_prediction, obs_fun, p_fun, pars)
 | 
| pars_opt | Free parameters a_ij to control the influence of the complexes | 
| perturbation_prediction | Simulated steady state perturbation data | 
| obs_fun | Observation function which returns the communicating species | 
| p_fun | Parameter transformation which returns different conditions | 
| pars | Parameters of the ODE model | 
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