get_vaf_correction: Computes the VAF correction factor for a table of mutations
In eyzhao/SignIT: What the Package Does (One Line, Title Case)
Description
Usage
Arguments
Details
Value
View source: R/get_vaf_correction.R
Description
The VAF correction factor adjusts the expected mean variant allele fraction
Usage
1
get_vaf_correction(mutation_table)
Arguments
mutation_table
The same mutation table used as input to
get_population_signatures.
Details
The correction factor is computed as
\frac{p}{C^{(t)} p + C^{(n)} (1-p)}
,
where p is the tumour content / purity, $C^(t)$ is the tumour
copy number, and $C^(n)$ is the normal copy number.
Value
Numeric vector of correction factors
eyzhao/SignIT documentation built on Dec. 6, 2019, 11:45 a.m.
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Description Usage Arguments Details Value
View source: R/get_vaf_correction.R
Description
The VAF correction factor adjusts the expected mean variant allele fraction
Usage
1 | get_vaf_correction(mutation_table)
|
Arguments
mutation_table |
The same mutation table used as input to
|
Details
The correction factor is computed as
\frac{p}{C^{(t)} p + C^{(n)} (1-p)}
,
where p is the tumour content / purity, $C^(t)$ is the tumour copy number, and $C^(n)$ is the normal copy number.
Value
Numeric vector of correction factors
R Package Documentation
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We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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