MethylMix_RemoveFlipOver: The MethylMix_RemoveFlipOver function

In gevaertlab/EpiMix: EpiMix: an integrative tool for the population-level analysis of DNA methylation

The MethylMix_RemoveFlipOver function

Description

Internal. The estimated densities for each beta component can overlap, generating samples that look like being separated from their group. This function re classifies such samples.

Usage

MethylMix_RemoveFlipOver(
  OrigOrder,
  MethylationState,
  classification,
  METdataVector,
  NrComponents,
  UseTrainedFlipOver = FALSE,
  FlipOverState = 0
)

Arguments

OrigOrder	order of sorted values in the methylation vector.
MethylationState	methylation states for this gene.
classification	vector with integers indicating to wich component each sample was classified into.
METdataVector	vector with methylation values from the cancer samples.
NrComponents	number of components in this gene.
UseTrainedFlipOver	.
FlipOverState	.

Value

Corrected vectors with methylation states and classification.

gevaertlab/EpiMix documentation built on July 20, 2023, 9:28 a.m.