imputeProteinConcentrations: Impute concentrations for proteins based on their total...

Description Usage Arguments Value Examples

View source: R/dataImputation.R

Description

Furthermore, missing protein molecular weights are also added.

Usage

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imputeProteinConcentrations(peptide.traces, protein.conc.estimates,
  protein.ids.file)

Arguments

peptide.traces

A long list format data.table of peptide traces.

protein.conc.estimates

A data.table holding the existing protein concentrations. It has the format:

  • protein_id

  • protein_mw

  • protein_concentration

protein.ids.file

A file path where the protein ids are stored for which a manual uniprot lookup has to be made.

Value

A data.table holding all proteins with their molecular weight and concentration.

Examples

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peptide.traces <- widePepTracesToLong(e4.peptide.traces.wide)
protein.ids.file <- '~/Desktop/proteinmw.txt'
imputeProteinConcentrations(peptide.traces, HEK293.protein.conc.estimates,
                            protein.ids.file)

hafenr/MACode documentation built on May 17, 2019, 2:24 p.m.