number.cells.detect.celltype: Cell sample size calculation for cell type identification

In heiniglab/scPower: Experimental design framework for scRNAseq population studies (eQTL and DE)

Cell sample size calculation for cell type identification

Description

Calculate required number of cells per individual to detect at least min.num.cells of a cell type with class frequency cell.type.frac for each of nSamples individual. with a probability of prob.cutoff

Usage

number.cells.detect.celltype(
  prob.cutoff,
  min.num.cells,
  cell.type.frac,
  nSamples
)

Arguments

prob.cutoff	Target power to detect the cell type
min.num.cells	Minimal number of the cells for the cell type of interest that should be detected
cell.type.frac	Frequency of the cell type of interest
nSamples	Sample size (number of individuals)

Value

Required number of cells per individual to reach the target power

heiniglab/scPower documentation built on Jan. 9, 2025, 12:13 p.m.