generate_homology_pathways: generate_homology_pathways

In humayun2017/SPAGI2: SPAGI2: Identification of active signalling pathways for cross-species by integrating gene expression and human protein interaction network

Description

This function generates homology pathways by altering the molecules of human pathway paths.

Usage

generate_homology_pathways(species.homology.data, pathway.path)

Arguments

species.homology.data	A list containing the homology data (i.e., homology table, homology matrix and species2 name) for the two species.
pathway.path	A list with human pathway path data where each sublist denotes a path of the pathway. This is used as a background data.

Details

This function generates homology pathways by altering the molecules of human pathway paths. The human pathway path data is automatically loaded with the package.

Value

This function returns the homology pathways by altering the pathway molecules by the homology molecules.

Examples

human.zebrafish.homology.data<-generate_homology_data(species1 = "hsapiens", species2 = "drerio")
zebrafish.homology.pathway.path<-generate_homology_pathways(species.homology.data = human.zebrafish.homology.data, pathway.path = pathway.path.new)
head(zebrafish.homology.pathway.path[[1]])

humayun2017/SPAGI2 documentation built on Aug. 5, 2020, 12:06 a.m.