tests/testthat/test_mut.R

context('Simulating mutations.')

# library(ape)
phy <- structure(list(edge = structure(c(11L, 13L, 19L, 19L, 13L, 18L,
                                         18L, 11L, 12L, 15L, 15L, 16L, 16L, 12L, 14L, 14L, 17L, 17L, 13L,
                                         19L, 1L, 2L, 18L, 3L, 4L, 12L, 15L, 5L, 16L, 6L, 7L, 14L, 8L,
                                         17L, 9L, 10L), .Dim = c(18L, 2L)),
                      edge.length = c(0.570743614638502, 0.743533392747197, 0.00315730974266033, 0.00315730974266033,
                                      0.718087960984797, 0.028602741505061, 0.028602741505061, 0.226254712324589,
                                      0.961297501178038, 0.129882103625732, 0.0568438422459096, 0.0730382613798221,
                                      0.0730382613798221, 0.924327430521649, 0.166852174282121, 0.116060928134785,
                                      0.0507912461473357, 0.0507912461473357),
                      tip.label = c("genome10","genome6", "genome5", "genome7", "genome9", "genome4", "genome1",
                                    "genome2", "genome8", "genome3"), Nnode = 9L),
                 class = "phylo", order = "cladewise")

m <- as.data.frame(phy$edge)
m$length <- phy$edge.length
norg <- 10
depth <- coalescent.intervals(phy)$total.depth
brti <- c(structure(rep(0, norg), names=1:norg), branching.times(phy))
ne <- 1e10
mu <- 5e-12
smat <- simurg:::.codon.subst.mat

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                  0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0,
                  0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 1, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1,
                  0, 0, 0), .Dim = c(10L, 359L), .Dimnames = list(c("genome1",
                                                                    "genome2", "genome3", "genome4", "genome5", "genome6", "genome7",
                                                                    "genome8", "genome9", "genome10"), c("gene1", "gene2", "gene3",
                                                                                                         "gene4", "gene5", "gene6", "gene7", "gene8", "gene9", "gene10",
                                                                                                         "gene11", "gene12", "gene13", "gene14", "gene15", "gene16", "gene17",
                                                                                                         "gene18", "gene19", "gene20", "gene21", "gene22", "gene23", "gene24",
                                                                                                         "gene25", "gene26", "gene27", "gene28", "gene29", "gene30", "gene31",
                                                                                                         "gene32", "gene33", "gene34", "gene35", "gene36", "gene37", "gene38",
                                                                                                         "gene39", "gene40", "gene41", "gene42", "gene43", "gene44", "gene45",
                                                                                                         "gene46", "gene47", "gene48", "gene49", "gene50", "gene51", "gene52",
                                                                                                         "gene53", "gene54", "gene55", "gene56", "gene57", "gene58", "gene59",
                                                                                                         "gene60", "gene61", "gene62", "gene63", "gene64", "gene65", "gene66",
                                                                                                         "gene67", "gene68", "gene69", "gene70", "gene71", "gene72", "gene73",
                                                                                                         "gene74", "gene75", "gene76", "gene77", "gene78", "gene79", "gene80",
                                                                                                         "gene81", "gene82", "gene83", "gene84", "gene85", "gene86", "gene87",
                                                                                                         "gene88", "gene89", "gene90", "gene91", "gene92", "gene93", "gene94",
                                                                                                         "gene95", "gene96", "gene97", "gene98", "gene99", "gene100",
                                                                                                         "gene101", "gene102", "gene103", "gene104", "gene105", "gene106",
                                                                                                         "gene107", "gene108", "gene109", "gene110", "gene111", "gene112",
                                                                                                         "gene113", "gene114", "gene115", "gene116", "gene117", "gene118",
                                                                                                         "gene119", "gene120", "gene121", "gene122", "gene123", "gene124",
                                                                                                         "gene125", "gene126", "gene127", "gene128", "gene129", "gene130",
                                                                                                         "gene131", "gene132", "gene133", "gene134", "gene135", "gene136",
                                                                                                         "gene137", "gene138", "gene139", "gene140", "gene141", "gene142",
                                                                                                         "gene143", "gene144", "gene145", "gene146", "gene147", "gene148",
                                                                                                         "gene149", "gene150", "gene151", "gene152", "gene153", "gene154",
                                                                                                         "gene155", "gene156", "gene157", "gene158", "gene159", "gene160",
                                                                                                         "gene161", "gene162", "gene163", "gene164", "gene165", "gene166",
                                                                                                         "gene167", "gene168", "gene169", "gene170", "gene171", "gene172",
                                                                                                         "gene173", "gene174", "gene175", "gene176", "gene177", "gene178",
                                                                                                         "gene179", "gene180", "gene181", "gene182", "gene183", "gene184",
                                                                                                         "gene185", "gene186", "gene187", "gene188", "gene189", "gene190",
                                                                                                         "gene191", "gene192", "gene193", "gene194", "gene195", "gene196",
                                                                                                         "gene197", "gene198", "gene199", "gene200", "gene201", "gene202",
                                                                                                         "gene203", "gene204", "gene205", "gene206", "gene207", "gene208",
                                                                                                         "gene209", "gene210", "gene211", "gene212", "gene213", "gene214",
                                                                                                         "gene215", "gene216", "gene217", "gene218", "gene219", "gene220",
                                                                                                         "gene221", "gene222", "gene223", "gene224", "gene225", "gene226",
                                                                                                         "gene227", "gene228", "gene229", "gene230", "gene231", "gene232",
                                                                                                         "gene233", "gene234", "gene235", "gene236", "gene237", "gene238",
                                                                                                         "gene239", "gene240", "gene241", "gene242", "gene243", "gene244",
                                                                                                         "gene245", "gene246", "gene247", "gene248", "gene249", "gene250",
                                                                                                         "gene251", "gene252", "gene253", "gene254", "gene255", "gene256",
                                                                                                         "gene257", "gene258", "gene259", "gene260", "gene261", "gene262",
                                                                                                         "gene263", "gene264", "gene265", "gene266", "gene267", "gene268",
                                                                                                         "gene269", "gene270", "gene271", "gene272", "gene273", "gene274",
                                                                                                         "gene275", "gene276", "gene277", "gene278", "gene279", "gene280",
                                                                                                         "gene281", "gene282", "gene283", "gene284", "gene285", "gene286",
                                                                                                         "gene287", "gene288", "gene289", "gene290", "gene291", "gene292",
                                                                                                         "gene293", "gene294", "gene295", "gene296", "gene297", "gene298",
                                                                                                         "gene299", "gene300", "gene301", "gene302", "gene303", "gene304",
                                                                                                         "gene305", "gene306", "gene307", "gene308", "gene309", "gene310",
                                                                                                         "gene311", "gene312", "gene313", "gene314", "gene315", "gene316",
                                                                                                         "gene317", "gene318", "gene319", "gene320", "gene321", "gene322",
                                                                                                         "gene323", "gene324", "gene325", "gene326", "gene327", "gene328",
                                                                                                         "gene329", "gene330", "gene331", "gene332", "gene333", "gene334",
                                                                                                         "gene335", "gene336", "gene337", "gene338", "gene339", "gene340",
                                                                                                         "gene341", "gene342", "gene343", "gene344", "gene345", "gene346",
                                                                                                         "gene347", "gene348", "gene349", "gene350", "gene351", "gene352",
                                                                                                         "gene353", "gene354", "gene355", "gene356", "gene357", "gene358",
                                                                                                         "gene359")))

nsites <- rep(100, dim(pm)[2])

muts <- simurg:::.sim_mut(pm = pm,
                         phy = phy,
                         nsites = nsites,
                         m = m,
                         depth = depth,
                         brti = brti,
                         ne = ne,
                         norg = norg,
                         mu = mu,
                         smat = smat)

segments <- apply(phy$edge, 1, paste, collapse = '-')

test_that('.sim_mut works',{
  expect_is(muts, 'list')
  expect_true(all(sapply(muts, class)=='list'))
  expect_true(class(unlist(muts))=='integer')
  sg <- unique(unlist(lapply(muts, names)))
  expect_true(all(sg%in%segments))
})
iferres/simba documentation built on July 31, 2019, 10:25 a.m.