Make.CLR: Make.CLR

Description Usage Arguments Value

Description

Takes a table of Features/OTUs/SVs and converts to centered log2 ratio abundances. See: Compositional analysis: a valid approach to analyze microbiome high-throughput sequencing data Gregory B. Gloor, Gregor Reid; Canadian Journal of Microbiology, 2016, 62:692-703, 10.1139/cjm-2015-0821 For information on CZM replacement see : Martin-Fernandez, J.A., Hron, K., Templ, M., Filzmoser, P., Palarea-Albaladejo, J. Bayesian-multiplicative treatment of count zeros in compositional data sets. Statistical Modelling 2015; 15 (2): 134-158.

Usage

1
Make.CLR(FEATURES, PRIOR, CZM)

Arguments

FEATURES

Table of feature/OTU/SV counts where Samples are columns, and IDs are row names

PRIOR

A numeric value to add before log transformation (default 0.5). *Ignored if CZM=TRUE

CZM

Should count zero multiplicative method be used instead of adding simple prior (TRUE/FALSE, defaults to FALSE)

Value

Table of CLR-normalized Abundances (log2)


jbisanz/MicrobeR documentation built on June 5, 2019, 7:53 p.m.