Run_LORS_Screening: Run_LORS_Screening 'Run_LORS_Screening' is a function to to...

In jdrhyne2/FastLORS: Joint Modeling for eQTL Mapping in R

Description

Run_LORS_Screening Run_LORS_Screening is a function to to apply the LORS-Screening Algorithm in Yang et al. (2013)

Usage

Run_LORS_Screening(Y, X, lambda = NULL)

Arguments

Y	gene expression matrix
X	matrix of SNPs
lambda	tuning parameter

Value

selectedSNPs the SNPs selected by LORS-Screening

Examples

##Example

## Generate some data
n <- 50
p <- 200
q <- 100
k <- 10
set.seed(123)
X <- matrix(rbinom(n*p,1,0.5),n,p)
L <- matrix(rnorm(n*k),n,k) %*% t(matrix(rnorm(q*k),q,k))
B <- matrix(0, ncol(X), ncol(L))
activeSNPs <- sort(sample(c(1:nrow(B)), 20))
for(i in 1:length(activeSNPs)){
genes_influenced <- sort(sample(c(1:ncol(B)),5))
B[activeSNPs[i], genes_influenced] <- 2
}
E <- matrix(rnorm(n*q),n,q)
Y <- X %*% B + L + E

selectedSNPs <- Run_LORS_Screening(Y, X)

jdrhyne2/FastLORS documentation built on March 5, 2020, 6:50 a.m.