Selects a set of top SNP based on p-value that are in minimal LD. Performs the same function as top_snps_pval_ld but with different input format.
1 2 3 | top_snps_pval_ld2_new(ld_files, snp_info_rds, snps, pval_cols = c(),
pval_thresh = Inf, r2_thresh = 0.01,
cores = parallel::detectCores() - 1)
|
ld_files |
List of h5 files containing pairwise ld. One for each chromosome. |
snp_info_rds |
RDS file with snp info |
snps |
List of snps |
pval_thresh |
Maximum pvalue |
r2_thresh |
r^2 threshold for pruning |
cores |
Number of cores to use |
pvals |
Vector of pvalues (optional) |
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