DVH.eud: Calculates Equivalent Uniform Dose for a 'dvhmatrix' object

Description Usage Arguments Value References

View source: R/dvh_mod.R

Description

Function that calculates the value of Equivalent Uniform Dose (EUD) for a dvhmatrix object. The formula to compute the equivalent uniform dose is

EUD=(Sum(Di^a * Vi/Vtot))^(1/a)

where i is the counter of volume bins in the structure and a is the parameter that relates the organs response to the serial or parallel physiological function of the organ. Usually parallel structures are organs that can suffer depletion of functional subunits up to a given threshold, as liver, lungs or kidneys. They are more sentitive to mean dose rather than hot spots and maximum dose levels delivered to the structure. On the other hand serial structures are organs more sensitive to hot-spots delivered in the volume, such as spinal cord.

Usage

1
DVH.eud(dvh, a = 1)

Arguments

dvh

A dvhmatrix class object

a

Value for parallel-serial correlation in radiobiological response

Value

A vector containing the values of EUD(s) for the given DVH(s)

References

Niemierko A. Reporting and analyzing dose distributions: a concept of equivalent uniform dose. Med Phys. 1997 Jan;24(1):103-10. PubMed PMID: 9029544.


kbolab/moddicom documentation built on Nov. 29, 2020, 9:11 p.m.